Association of the glycoxidative stress marker pentosidine with equine laminitis
نویسندگان
چکیده
منابع مشابه
Laminitis and the equine metabolic syndrome.
Although much has been written about laminitis in the context of its association with inflammatory processes, recognition is growing that most cases of laminitis examined by veterinarians in private practice are those associated with pasture grazing, obesity, and insulin resistance (IR). The term 'endocrinopathic laminitis' has been adopted to classify the instances of laminitis in which the or...
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Vasodilation precedes the development of carbohydrate overload laminitis. Circulating laminitis trigger factors activate lamellar enzymes, which lyse the attachments between the distal phalanx and the inner hoof wall. The clinical signs of laminitis occur when the lamellar architecture disintegrates. The amount of pain correlates with the extent of lamellar pathology. A substance produced by St...
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Over the past 20 yr, extensive research efforts as well as clinical experience has greatly increased our knowledge base of equine laminitis. Our present understanding of the disease is that there is failure of the lamellar attachment between the distal phalanx and hoof wall. This, in turn, initiates a sequence of events ranging from no permanent structural damage to loss of the hoof capsule. Af...
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چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولNeuropathic changes in equine laminitis pain.
Laminitis is a common debilitating disease in horses that involves painful disruption of the lamellar dermo-epidermal junction within the hoof. This condition is often refractory to conventional anti-inflammatory analgesia and results in unremitting pain, which in severe cases requires euthanasia. The mechanisms underlying pain in laminitis were investigated using quantification of behavioural ...
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ژورنال
عنوان ژورنال: The Veterinary Journal
سال: 2013
ISSN: 1090-0233
DOI: 10.1016/j.tvjl.2012.10.030